From TVguide.com:
A sudden plane crash leaves at least 48 survivors stranded on a jungle island, forced to scavenge for survival from the wreckage of the plane. As they get their bearings and pin their hopes on a quick rescue, the band of strangers begin to learn the island holds deep and dark secrets. A group of strong-willed survivors: Jack, a surgical doctor; Charlie, a former rock star; and the enigmatic Kate venture into the dark heart of the jungle to try and recover the airplane transceiver. But even heroes have secrets, as the survivors will soon learn.